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Current SVLSF investmentsPlease see below a list of all our current investments by fundTo go to individual portfolio companies websites please click on company logo. 
Genosis: UKFirst investment: 1999 - Start Up Male and female home fertility diagnostics. 
MedNova: IrelandFirst investment: 1996 - Start Up Devices for interventional radiology and cardiology. 
Metris Therapeutics: UKinvestment SVLSF I: 1998 - Start Up investment SVLSF II: 2000 Treatment of gynaecological disorders. 
MicroMed: USFirst investment: 1998 - Early Stage Left ventricular assist devices 
Micromet: GermanyFirst investment: 1998 - Start Up Drug discovery using novel protein drugs 
Achillion: USFirst investment: 2000 - Start Up Dedicated to bringing important new treatments to patients with infectious disease. Anti-infective drug development. 
AcuFocus: USFirst investment: 2001 - Seed Implantable contact lens. 
Affibody: SwedenFirst investment: 2001 - Early Stage Molecular imaging and targets therapeutics. 
AllianceCare At Home: USFirst investment: 2000 - Start Up Personal in-home care. Formerly known as Sunrise at Home Assisted Living. 
Cadent Technologies: USFirst investment: 2000 - Early Stage Provides 3D digital information services that replace the use of physical models in denistry. 
CardioFocus: USFirst investment: 1999 - Early Stage Laser based ablation devices. 
Cellzome: GermanyFirst investment: 2001 - Start Up Proteomics technology for target and lead identification, and a drug discovery program in Alzheimer's Disease. 
Cerebral Vascular Applications: USFirst investment: 2000 - Seed Minimally invasive atrial fibrillation devices. Funded through the innovation factory 
Cognis: LuxembourgFirst investment: 2001 - Buy Out Speciality chemicals. Products and solutions for personal care, home care and modern nutrition. 
Confluent Surgical: USFirst investment: 1999 - Early Stage Biomaterials for adhesion prevention and vascular embolics. 
IHG Holdings: USFirst investment: 2001 - Buy Out Preferred provider organization.(Formerly known as Interplan). 
Ingenium: GermanyFirst investment: 2000 - Early Stage Functional genomics and drug development. 
Insulet: USFirst investment SVLSF II: 2001 - Start Up First investment SVLSF III: 2004 - Late Stage Disposable insulin infusion devices for diabetes. 
Liposonix: USFirst investment SVLSF II: 2001 - Seed First investment SVLSF III: 2003 - Seed Focused ultrasound alternative to liposuction.. Funded through the innovation factory. 
Lorantis Holdings: UKFirst investment SVLSF II: 2000 - Start Up First investment SVLSF III: 2003 - Early Stage Immunology based drugs. 
MDeverywhere: USFirst investment: 2001 - Early Stage Physician charge capture software. Metris Therapeutics: UKFirst investment SVLSF I: 1998 - Start Up First investment SVLSF II: 2000 - Start Up Treatment of gynaecological disorders. 
Oxagen: UKFirst investment: 2000 - Expansion Clinical genomics. 
Phase Forward: USFirst investment: 1999 - Expansion Web-based information technology for clinical trials management. 
Quickstudy Radiology: USFirst investment: 2000 - Start Up Radiology and web-based technology service company. 
Solexa: UKFirst investment: 2001 - Start Up Ultra high throughput DNA sequencing. 
Trine Pharmaceuticals: USFirst investment: 2001 - Expansion Anti-infective drug discovery. (Formerly known as Essential Therapeutics 'ETRX'). 
Alantos Pharmaceuticals: USFirst investment: 2003 - Early Stage Combinatorial chemistry focused upon lead discovery and optimization. (Previously known as Therascope). 
Alba Therapeutics: USFirst investment: 2005 - Early Stage For the treatment of inflammatory and immune mediated diseases. Alinea: US First investment: 2005 - Expansion Alinea is a spinout that will develop a PTP1b inhibitor for insulin resistance. Allegiance Hospice Group: US First investment: 2005 - Start Up Hospice services in New England. Aquesys: US First investment: 2006 - Early Stage Develops a device treatment for primary open angle glaucoma using a soluble duct that functions to reduce intraocular pressure by creating a drainage pathway for excess fluid to flow from the anterior chamber into the sub conjunctiva. 
Archemix: USFirst investment: 2002 - Early Stage Develops aptamers as a new class of direct therapeutics for the prevention and treatment of chronic and acute disease. 
Avera Pharmaceuticals: USFirst investment: 2004 - Early Stage Development and commercialization of novel pharmaceutical compounds for treatment of neurologic and psychiatric disorders. 
Cellutions: USFirst investment: 2004 - Seed Minimally invasive treatment of cellulite. 
CHF Solutions: USFirst investment: 2005 - Expansion Mechanical pump filter system to remove fluid from patients with congestive heart failure. 
Concentric Medical: USFirst investment: 2003 - Expansion Interventional neurovascular products for stroke treatment. 
Dynogen Pharmaceuticals: USFirst investment: 2004 - Early Stage Genito-urinary and gastro-intestinal disorders using neuroscience-based pharmaceutical drugs. EBR Systems: US First investment: 2005 - Early Stage EBR Systems, Inc. is an early-stage development venture pursuing novel approaches in cardiac rhythm management. 
Entellus: USFirst investment: 2006 - Early Stage Entellus is focused on providing unique solutions to the unmet clinical needs of the ENT physician through the development of innovative device technology. 
ESBATech: SwitzerlandFirst investment: 2006 - Early Stage ESBATech is a preclinical stage drug discovery company exploiting a novel platform for antibody fragment discovery.  Fundamental Applied Biology, Inc.: US First investment: 2006 - Early Stage Fundamental Applied Biology (FAB), Inc. mission is enable the production of low-cost, high quality rapidly developed products and technology for protein pharmaceuticals and innovative vaccines. 
Gyros: SwedenFirst investment: 2002 - Start Up Microfluidic tools for laboratory applications.
Insulet: USFirst investment SVLSF II: 2001 - Start Up First investment SVLSF III: 2004 - Expansion Disposable insulin infusion devices for diabetes. 
Intranasal Therapeutics: USFirst investment: 2006 - Early Stage Intranasal Therapeutics, Inc. ("ITI") is a specialty pharmaceutical company focused on developing innovative, nasally delivered pharmaceutical products with a particular focus on drugs treating pain and CNS-related disorders.
Liposonix: USinvestment SVLSF II: 2001 - Seed investment SVLSF III: 2003 - Seed Focused ultrasound alternative to liposuction.. Funded through the innovation factory.
Lorantis: UKFirst investment SVLSF II: 2000 - Start Up First investment SVLSF III: 2003 - Early Stage Immunology based drugs. 
Lux Bioscience: USFirst investment: 2006 - Seed Opthalmic drugs 
Medifacts International: USFirst investment: 2004 - Expansion Cardiovascular core lab and contract research organization. 
Mpex Pharmaceuticals: USFirst investment: 2005 - Early Stage Development of new anti-bacterial drugs that meet the growing clinical need created by multi-drug resistant bacterial pathogens. 
Neovista: USFirst investment: 2003 - Seed Developing a technology to irradiate the back of the eye for treatment of Wet AMD. 
Neurotech: USFirst investment: 2006 - Early Stage Neurotech is a biotechnology company dedicated to the development of sight-saving therapeutics for chronic retinal diseases. 
OsteoLign: USFirst investment: 2005 - Seed OsteoLign is an early stage company founded by The Innovation Factory with a minimally invasive solution for long bone fractures. 
Patient Care: USFirst investment: 2002 - Buy Out One of the largest US independent home health agencies. ReShape: US First investment: 2005 - Seed Concept-stage company developing a medical device based treatment for obesity. (Previously known as Abdominis, Inc).  Sadra Medical: USFirst investment: 2003 - Seed A company developing a medical device for the percutaneous replacement of aortic valves. 
Sapphire Therapeutics: USFirst investment: 2004 - Early Stage Developing compounds for treatment of oncologic and metabolic diseases. (Formerly known as Rejuvenon). 
Socios Mayores en Salud: USFirst investment: 2006 - Expansion Puerto Rican managed care organization. 
Spinal Kinetics: USFirst investment: 2005 - Early Stage Spinal Kinetics is a development stage company dedicated to providing innovative, therapeutic devices for the treatment of degenerative diseases of the spine. 
Synarc: USFirst investment: 2004 - Late Stage Central Radiology service dedicated exclusively to clinical trials.
EUSA Pharma : USFirst investment: 2007 - Early Stage A specialty pharmaceutical company focused on developing and marketing innovative products for the worldwide hospital market.
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