SV Life Sciences

Portfolio

SV Life Sciences currently advises or manages five funds with capital commitments of approximately $2.0 billion which primarily invest amounts of between $1m and $40m in North America and Europe, but will consider innovative investments in other regions. This part of our website provides a brief summary of each portfolio company with links to their websites where possible.

105 matching investments found

Company	Country	Stage	Sector	Year
Achillion Pharmaceuticals	US	Start Up	Biotechnology Biopharmaceuticals	2000
(NASDAQ: ACHN). Achillion, based in New Haven, CT, is focused on the discovery, development and commercialization of innovative small molecule therapeutics for the treatment and/or prevention of serious infections associated with drug resistant viruses or bacteria.
Aderis Pharmaceuticals	US	Expansion	Biotechnology Biopharmaceuticals	2001
Aderis Pharmaceuticals was a Cardiovascular, renal and neurological disease focused therapeutics focused upon making a significant difference to people living with cardiovascular, renal and neurological diseases.
Affibody	Sweden	Early Stage	Biotechnology Biopharmaceuticals	2001
Affibody is a biotech company that uses unique affinity ligands to develop products for molecular imaging, targeted therapy and biotechnology applications. The lead product is a Her2 affibody for clinical imaging in breast cancer, and its pipeline includes other oncology imaging affibodies. In addition, affibodies are sold as research reagents and for use in protein separations.
Alantos Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2003
Sold to Amgen in June 2007. Alantos was a chemistry-driven company seeking to discover and develop drugs targeted at osteoarthritis and inflammatory processes. The company attempts to fast follow others to reduce risk.
Alba Therapeutics	US	Early Stage	Biotechnology Biopharmaceuticals	2005
Alba based in Baltimore, MD, is focused on the development and commercialization of pharmaceuticals for the treatment of inflammatory and immune mediated diseases. Alba's technology provides the ability to transiently open or close internal barriers such as the intestinal mucosa. Alba is applying its technology to develop treatments for celiac disease and other autoimmune conditions.
Alinea Pharmaceuticals	US	Expansion	Biotechnology Biopharmaceuticals	2005
Dedicated to developing and commercializing pharmaceuticals for the treatment of diabetes and related metabolic disorders.
Allegiance Hospice Group	US	Start Up	Healthcare Services	2005
Allegiance Hospice is based in Lowell, MA, focused on providing hospice services to patients primarily in long- term care facilities within the New England market.
AllianceCare	US	Start Up	Healthcare Services	2000
AllianceCare, based in Boynton Beach, FL, is a senior healthcare provider of Private Duty Home Care, Skilled Home Health, Physician Housecalls and Rehab. The Company currently offers services through 17 branch offices in 3 states.
Allos Therapeutics	US	Early Stage	Biotechnology Biopharmaceuticals	1998
Allos Therapeutics was developing and commercializing innovative small molecule therapeutics for the treatment of cancer.
Antiva	UK	Start Up	Biotechnology Biopharmaceuticals	2010
Antiva, is a spin out business from Vantia Therapeutics (www.vantiatherapeutics.com)and alongside that business focuses on leading research into improving clinical treatments through development and commercialization of innovative medicines.
Argonaut Technologies	US	Expansion	Medical Devices Instrumentation	1999
Argonaut developed a chemistry instrumentation for accelerated synthesis of novel organic molecules. Bought by Biotage after our exit.
Auxilium Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2001
Auxilium developed a male hormone replacement therapy.
Avera Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2004
Avera is based in San Diego, CA and focused on the development of small molecule drugs for the treatment of diseases affecting the central nervous system (CNS). Key programs are Alzheimer's disease, schizophrenia associated cognition deficits, IBS, and OAB, and developing an ultra-short acting anaesthesia compound.
Axys Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	1994
Axys developed a protease-inhibitor based products for cancer & inflammatory diseases.
Broadlane	US	Development	Healthcare Services	2009
Broadlane is a group purchasing organization ("GPO") focused on the acute care market. Broadlane provides technology-enabled services to assist hospitals in reducing supply costs and improve purchasing efficiency.
Cadent Technologies	US	Early Stage	Healthcare Services	2000
Cadent is based in Carlstadt, NJ and has developed proprietary computer aided design (CAD/CAM) applications for the orthodontist and dental markets, which are deployed via a web-based service model on a pay per use basis.
Cardiac Support Systems	US	Seed	Medical Devices Instrumentation	2000
Cardiac Support Systems was an innovation factory company.
CardioMind	US	Early Stage	Medical Devices Instrumentation	2007
Cardiomind has developed an innovative stent and stent delivery system for small, difficult-to-access vessels.
Celldex/Lorantis	UK	Start Up	Biotechnology Biopharmaceuticals	2000
Celldex merged with the quoted company Avant Immunotherapeutics (ticker:'AVAN') in March 2008. Celldex, formerly a wholly owned subsidiary of Medarex Inc., merged with Lorantis Ltd in 2005. Celldex pursues immunological approaches to the treatment of cancers, infectious disease and immunological disorders.
Celldex/Lorantis	UK	Seed	Biotechnology Biopharmaceuticals	2003
Celldex merged with the quoted company Avant Immunotherapeutics (ticker:'AVAN') in March 2008. Celldex, formerly a wholly owned subsidiary of Medarex Inc., merged with Lorantis Ltd in 2005. Celldex pursues immunological approaches to the treatment of cancers, infectious disease and immunological disorders.
Cellutions	US	Seed	Medical Devices Instrumentation	2004
Cellutions (TIF Company), based in Duluth, GA, (is developing a minimally invasive approach for addressing cellulite and its appearance on the skin.
Cellzome	Germany	Start Up	Biotechnology Biopharmaceuticals	2001
Cellzome is a drug discovery company building a R&D pipeline in chronic diseases by leveraging its unique drug proteomics engine. The business is based in Heidelberg, Germany and Cambridge, UK.
Cerebral Vascular Applications	US	Seed	Medical Devices Instrumentation	2000
Cerebral Vascular Applications (TIF Company) has developed a set of minimally invasive tools for atrial appendage sealing for stroke prevention.
Cerebrus	UK	Start Up	Biotechnology Biopharmaceuticals	1995
Cerebrus CNS drug discovery (Acquired by Nigra, which was then bought by Vernalis)
CHF Solutions	US	Expansion	Medical Devices Instrumentation	2005
CHF is based in Brooklyn Park, MN and has developed a mechanical pump/filter system to remove excess fluid from patients with acute de-compensated congestive heart failure. The product has US 510k clearance and is CE marked for both in-patient hospital care and out-patient clinic use.
Cognis	Luxembourg	Buyout	Biotechnology Biopharmaceuticals	2001
Cognis is a global supplier of innovative speciality chemicals for the cosmetics, detergents and cleaners industries and nutrional ingredients to the food and healthcare markets.
Concentric Medical	US	Expansion	Medical Devices Instrumentation	2003
Concentric is based in Mountain View, CA and is designing and developing products to open the blood pathway for ischemic stroke patients. Their first device, the MERCI Retriever®, removes clots associated with ischemic strokes.
Confluent Surgical	US	Early Stage	Medical Devices Instrumentation	1999
Confluent Surgical was a biomaterials for adhesion prevention and vascular embolics.
Coral Therapeutics	US	Start Up	Healthcare Services	1994
Coral was a provision of blood handling services to hospitals.
Cytomed	US	Early Stage	Biotechnology Biopharmaceuticals	1997
Cytomed was a leukotriene inhibitors for asthma (Acquired by LeukoSite Inc and then by Millenium).
Dynogen Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2004
Dynogen is a neuroscience-based company focused on genito-urinary (GU) and gastro-intestinal (GI) disorders. The company is using its knowledge of neurology and GU/GI disorders to build a pipeline of clinical candidates.
EasyChem	US	Seed	Healthcare Services	2000
EasyChem was a B2B chemical e-commerce electronic marketplace.
eMed Technologies	US	Expansion	Healthcare Services	2000
eMed Delivered medical images over the internet.
ESBATech	Switzerland	Early Stage	Biotechnology Biopharmaceuticals	2006
Sold to Alcan in September 2009. ESBATech is a preclinical stage drug discovery company that intends to refocus the business to build a world class Ophthalmology company on the back of an attractive, proprietary antibody fragment platform which can deliver uniquely stable, soluble and monomeric fragments and compelling data on penetration of these fragments into the eye following topical treatment.
Eunoe	US	Expansion	Medical Devices Instrumentation	2003
Eunoe was a treatment of neurological disorders through cerebrospinal fluid management (CSF).
Euro Dentalversand	Germany	Buyout	Healthcare Services	2000
Euro was mail order dental consumables.
EUSA Pharma	UK	Expansion	Biotechnology Biopharmaceuticals	2007
EUSA Pharma (EUSA) is a fast growing, transatlantic specialty pharma company developing and commercializing a range of prescription products in pain, oncology and critical care. Currently, the Company has eight products on the market.
Expand Sante	France	Seed	Healthcare Services	2000
Expand Sante was a French pharmaceutical contract sales organisation.
Eyetech Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2000
Eyetech was bought by OSI Pharmaceuticals after our exit through public markets. Opthalmolological drug development.
Geltex Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	1998
Geltex developed novel non-absorbed pharmaceuticals. Geltex was acquired by Genzyme Corporation after our exit through public markets.
General Surgical Innovations	US	Early Stage	Medical Devices Instrumentation	1995
General Surgical Innovations is a minimally invasive approach to hernia repair and incontinence (purchased by United States Surgical).
Genosis	UK	Start Up	Medical Devices Instrumentation	1999
Genosis has developed home use diagnostic devices to assess fertility in couples of childbearing age. Genosis products - Fertell, which provide both male and female tests, are available over the counter in the UK and the US and provide couples with the tools required to assess their fertility in the privacy of their homes.
GlycoFi	US	Start Up	Biotechnology Biopharmaceuticals	2002
Sold to Merck in May 2006. GlycoFi was a production and engineering of therapeutics proteins.
Gyros	Sweden	Start Up	Medical Devices Instrumentation	2002
Gyros, located in Uppsala, Sweden, has developed a proprietary microfluidics technology for processing and analysis of proteins and blood samples. Laboratory processes are integrated into a client specific disc (CD) format. The CD is processed and its contents analysed on software controlled instrumentation.
Heritage Health Systems	US	Early Stage	Healthcare Services	1995
Heritage was a physician practice.
Homecare Homebase	US	Late Stage	Healthcare Services	2011
HCHB offers a comprehensive integrated web-based software solution to improve the clinical, operational and financial success of homecare and hospice agencies.
IHG Holdings	US	Buyout	Healthcare Services	2001
IHG was a preferred provider organization. (Formerly known as Interplan).
Ikano Therapeutics	US	Early Stage	Biotechnology Biopharmaceuticals	2006
ITI is a specialty pharmaceutical company focused on developing innovative, nasally delivered pharmaceutical products with a particular focus on drugs treating pain and CNS-related disorders for which there is proven, unmet patient need.
Incyte Pharmaceuticals	UK	Start Up	Biotechnology Biopharmaceuticals	1996
Functional genomics Acquired by Incyte Pharmaceuticals in September 1999.
Ingenium	Germany	Early Stage	Biotechnology Biopharmaceuticals	2000
Ingenium was a functional genomics and drug development company.
Insulet	US	Start Up	Medical Devices Instrumentation	2001
Insulet based in Bedford, MA, Insulet is designing and developing products that provide superior treatment for people with diabetes. The Company's first commercial product is a wireless 3-day insulin pump.
Itero Biopharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2007
Itero is an early stage company focused on the development and commercialization of differentiated biosimilar and second generation protein products that serve niche markets.
JC Nationwide	US	Buyout	Healthcare Services	1995
JC Nationwide was a physician recruitment agency.
Juvaris BioTherapeutics	US	Early Stage	Biotechnology Biopharmaceuticals	2009
Developing novel, adjuvanted vaccines and immunotherapeutics to treat infectious disease and cancer.
Kinetix Pharmaceuticals	US	Start Up	Biotechnology Biopharmaceuticals	1999
Kinase targeted drug discovery. Acquired by Amgen in October 2000.
KuDOS Pharmaceuticals	UK	Start Up	Biotechnology Biopharmaceuticals	1999
KuDOS was an oncology drug development company. Acquired by Astra Zeneca in December 2005.
Leica Microsystems	Germany	Buyout	Medical Devices Instrumentation	1998
Leica Manufactured and marketed microscopes and neurosurgical equipment.
LenSx Lasers, Inc	US	Start Up	Medical Devices Instrumentation	2008
LenSx was initially backed by SVLS as a start-up company developing an integrated femtosecond laser system to perform phacolysis (for cataract lens extraction), alignment of premium intraocular lens (IOL) placement, and corneal incisions for treating astigmatism, all of which will be used during a single comprehensive cataract procedure.
LeukoSite	US	Start Up	Biotechnology Biopharmaceuticals	1994
LeukoSite was a treatment of Inflammatory diseases and cancer. Acquired by Amgen in October 1999.
Link Medicine	US	Early Stage	Biotechnology Biopharmaceuticals	2008
Link Medicine is a clinical stage company spun out of Harvard University working on disease-modifying therapies for neurodegenerative diseases.
LipoSonix	US	Seed	Medical Devices Instrumentation	2001
LipoSonix based in Bothell, WA, was developing a product to use non-invasive, high intensity focused ultrasound to ablate unwanted subcutaneous cells as a non-invasive alternative to liposuction for body sculpting. Funded through the innovation factory.
Lux Biosciences	US	Seed	Biotechnology Biopharmaceuticals	2006
Lux is developing drugs for ophthalmic diseases. Their lead product is LX211, an oral drug for the treatment of uveitis.
Mdeverywhere	US	Early Stage	Healthcare Services	2001
Mdeverywhere based in Hauppauge, NY with operations in New Dehli, India, is an outsourced physician billing company.
MedNova	Ireland	Start Up	Medical Devices Instrumentation	1996
MedNova was a device for interventional radiology and cardiology.
Metris Therapeutics	UK	Start Up	Biotechnology Biopharmaceuticals	2000
Metris is a women's healthcare company that is developing drugs for the treatment of chronic gynecological and menstrual conditions.
Micromass	UK	Buyout	Medical Devices Instrumentation	1996
Micromass was a minimally invasive approach to hernia repair and incontinence (purchased by Waters).
MicroMed	US	Early Stage	Medical Devices Instrumentation	1998
MicroMed based in Houston, TX, has developed an implantable pump for use as a Left Ventricular Assist Device (LVAD) to aid the heart's pumping action in patients suffering from congestive heart failure.
Micromet	US	Start Up	Biotechnology Biopharmaceuticals	1998
(NASDAQ: MITI) Micromet, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of innovative antibody-based therapies for the treatment of cancer.
MindFrame	US	Seed	Medical Devices Instrumentation	2007
MindFrame is a seed stage company formed out of Intersect Partners developing a novel mechanical device for the treatment of ischemic stroke.
Mpex Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	2005
Mpex based in San Diego, CA, is focused on the discovery and development of new-antibacterial drugs that meet the growing clinical need created by multi-drug resistant bacteria. Mpex has identified several approaches to increase the effectiveness of existing antibiotics and decrease the incidence of drug resistance to these antibiotics. Mpex's first product will be an inhaled antibiotic for serious lung infections.
NeoVista	US	Seed	Medical Devices Instrumentation	2003
NeoVista, based in Mountain View, CA, is developing a unique technology to arrest vascular proliferation in the back of the eye with localized radiation for treatment of wet age related macular degeneration (AMD).
NeurogesX	US	Pipe	Biotechnology Biopharmaceuticals	2007
NeurogesX is developing novel topical products to relieve chronic pain and improve quality of life.
Nexan	UK	Start Up	Medical Devices Instrumentation	1996
Nexan was a remote telemonitoring devices.
NovaLign	US	Seed	Medical Devices Instrumentation	2005
NovaLign, based in Duluth, GA, is developing a minimally invasive implant for long bone fixation. Formerly known as OsteoLign.
OMS Foundations	US	Early Stage	Healthcare Services	1998
OMS Foundations was an oral maxillofacial physician practice management.
Orchid Chemicals and Pharmaceuticals	India	Expansion	Biotechnology Biopharmaceuticals	1999
Orchid manufactured bulk generic pharmaceuticals.
Orthovita	US	Early Stage	Medical Devices Instrumentation	1997
Orthovita was a novel bone substitute materials company.
Patient Care	US	Buyout	Healthcare Services	2002
Patient Care based in Orange, NJ, is one of the largest independent home health agencies.
Pelton & Crane	US	Buyout	Healthcare Services	1997
Pelton & Crane developed sterilization equipment.
Phase Forward	US	Expansion	Healthcare Services	1999
Phase Forward was a web-based information technology for clinical trials management.
Physicians Dialysis	US	Buyout	Healthcare Services	2001
Physicians Dialysis was a consolidator of renal dialysis centers (Purchased by DaVita).
PowderMed	UK	Early Stage	Biotechnology Biopharmaceuticals	2004
Sold to Pfizer in October 2006. PowderMed developed therapeutic DNA vaccines in the areas of chronic viral diseases and cancer.
Quantum Dot	US	Early Stage	Biotechnology Biopharmaceuticals	2000
Quantum Dot developed nanocrystal biological reagents.
Quick Study Radiology	US	Start Up	Healthcare Services	2000
QSR based in St. Louis, MO, sells comprehensive digital imaging services to community hospitals and imaging centers. The company integrates, manages and supports clinical and data systems for customers with a focus on underserved small and secondary city locations.
RespiVert	UK	Start Up	Biotechnology Biopharmaceuticals	2007
Sold to J&J in June 2010. RespiVert is a discovery company focused on Chronic obstructive pulmonary disease ('COPD') and severe asthma. The company's goal is to develop novel inhaled and intranasal drugs for respiratory disorders with high unmet medical need and high commercial potential based on novel insights on biology and chemistry.
Rinat Neuroscience	US	Early Stage	Biotechnology Biopharmaceuticals	2003
Sold to Pfizer in April 2006. Rinat developed proteins for the treatment of diseases and disorders of the nervous system.
Sadra Medical	US	Seed	Medical Devices Instrumentation	2009
Sadra Medical has developed a second generation Percutaneous Aortic Valve Replacement (PAVR) implant and delivery system for the treatment of aortic stenosis.
Sapphire Therapeutics	US	Early Stage	Biotechnology Biopharmaceuticals	2004
Acquired by Helsinn in February 2009. Helsinn is developing small molecule drugs based on the biology of ghrelin,a gut peptide known to stimulate appetite. The lead compound is in Ph II for cancer cachexia; a second compound has completed an initial clinical study and is moving toward Ph II for post-operative ileus. Additional indications are being explored for follow-on compounds. Formerly known as Rejuvenon.
Shire Pharmaceuticals	US	Early Stage	Biotechnology Biopharmaceuticals	1994
Ticker: SHP LN Shire Pharmaceuticals - speciality pharma company formed on osteoporosis and Alzheimer's disease.
Sirona Dental Systems	Germany	Buyout	Medical Devices Instrumentation	1997
Sirona was a dental equipment manufacturer.
Socios Mayores en Salud	US	Expansion	Healthcare Services	2006
Socios Mayores en Salud provides health insurance to seniors in Puerto Rico through a Medicare Advantage plan that operates similar to traditional managed care organizations.
Solexa	UK	Start Up	Biotechnology Biopharmaceuticals	2001
Sold to Illumina ILMN. Solexa used ultra high throughput DNA sequencing.
Strides Arcolab	India	Expansion	Biotechnology Biopharmaceuticals	1997
Strides Arcolab was a manufacturer of generic pharmaceuticals.
Synarc	US	Late Stage	Healthcare Services	2004
Synarc provides centralized medical imaging services and international subject-recruitment facilities dedicated exclusively to global clinical trials.
The Corner Pharmacy	US	Development	Healthcare Services	2010
An owner and operator of hospital-based retail pharmacies through joint ventures with hospital systems.
Third Wave Technologies	US	Expansion	Biotechnology Biopharmaceuticals	1999
Third Wave developed products for analysing genetic variations.
TLC Vision	US	Expansion	Healthcare Services	1995
TLC Vision was a service provider for laser-based ophthalmic surgery. Formerly known as Laservision.
Triangle Pharmaceuticals	US	Start Up	Biotechnology Biopharmaceuticals	1995
Triangle Pharmaceuticals was an antiviral and anticancer drug development company. Acquired by Gilead in January 2003.
Trine Pharmaceuticals	US	Expansion	Biotechnology Biopharmaceuticals	2001
Trine, formerly Essential Therapeutics Inc., in-licenses, develops and plans to commercialize new classes of pharmaceutical products focused on renal, metabolic and GI clinical areas.
US Renal Care	US	Expansion	Healthcare Services	2005
US Renal Care(USRC) based in Dallas, TX, provides dialysis services to patients with end stage renal disease (ESRD) through the ownership and management of freestanding dialysis clinics. The company partners with local nephrologists in secondary markets underserved by dialysis consolidators.
Vanguard Medica (Vernalis)	UK	Early Stage	Biotechnology Biopharmaceuticals	1995
Vanguard Medica was an antiviral and anticancer drug development company. (Acquired by Vernalis)
Versicor	US	Expansion	Biotechnology Biopharmaceuticals	1999
Versicor was a drug development company for infectious diseases (Changed name to Vicurion Pharmaceuticals in 2003)
Vintage BioMed	US	Seed	Healthcare Services	1996
Vintage BioMed was a capital equipment leasing and maintenance company.
Vitalize Consulting Solutions	US	Buyout	Healthcare Services	2007
Vitalize Consulting Solutions, Inc. provides the highest quality clinical and business solutions to healthcare organizations across the United States and Canada. Their main focus is in the areas of application implementation and enhancement, process optimization, interfaces, project management, technology and integration, training and knowledge transfer.
X2-Pharma	Germany	Seed	Biotechnology Biopharmaceuticals	2008
X2-Pharma is a biopharmaceutical company dedicated to the discovery and development of small molecule pharmaceuticals for the treatment of inflammatory diseases.

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