SVLSF II closed in 1999 with total commitments of $280 million (plus $30 million of co-investments committed by partners and individuals affiliated with SVLS).
As at 31 December 2012, the fund had invested $338 million (including re-investment) in 36 portfolio companies.
| Company | Country | Stage | Sector | Year |
|---|
Achillion Pharmaceuticals | US | Start Up | Biotechnology Biopharmaceuticals | 2000 |
| (NASDAQ: ACHN).
Achillion, based in New Haven, CT, is focused on the discovery, development and commercialization of innovative small molecule therapeutics for the treatment and/or prevention of serious infections associated with drug resistant viruses or bacteria. |
AcuFocus | US | Seed | Medical Devices Instrumentation | 2001 |
| AcuFocus, based in Irvine, CA, is developing an implantable corneal in-lay for the correction of presbyopia. |
Aderis Pharmaceuticals | US | Expansion | Biotechnology Biopharmaceuticals | 2001 |
| Aderis Pharmaceuticals was a Cardiovascular, renal and neurological disease focused therapeutics focused upon making a significant difference to people living with cardiovascular, renal and neurological diseases. |
Affibody | Sweden | Early Stage | Biotechnology Biopharmaceuticals | 2001 |
| Affibody is a biotech company that uses unique affinity ligands to develop products for molecular imaging, targeted therapy and biotechnology applications. The lead product is a Her2 affibody for clinical imaging in breast cancer, and its pipeline includes other oncology imaging affibodies. In addition, affibodies are sold as research reagents and for use in protein separations. |
AllianceCare | US | Start Up | Healthcare Services | 2000 |
| AllianceCare, based in Boynton Beach, FL, is a senior healthcare provider of Private Duty Home Care, Skilled Home Health, Physician Housecalls and Rehab. The Company currently offers services through 17 branch offices in 3 states. |
Argonaut Technologies | US | Expansion | Medical Devices Instrumentation | 1999 |
| Argonaut developed a chemistry instrumentation for accelerated synthesis of novel organic molecules. Bought by Biotage after our exit. |
Atopix Therapeutics and Oxagen | UK | Early Stage | Biotechnology Biopharmaceuticals | 2000 |
| Atopix Therapeutics and Oxagen are related through an investment made in to Atopix in Q1 2012 and an agreement with Oxagen to allow Atopix to continue to develop the technology started by Oxagen. The companies are based in Oxford, UK. The companies are developing drugs targeted at inflammatory and metabolic diseases.
www.atopixtherapeutics.co.uk / www.oxagen.co.uk |
Auxilium Pharmaceuticals | US | Early Stage | Biotechnology Biopharmaceuticals | 2001 |
| Auxilium developed a male hormone replacement therapy. |
Cadent Technologies | US | Early Stage | Healthcare Services | 2000 |
| Cadent is based in Carlstadt, NJ and has developed proprietary computer aided design (CAD/CAM) applications for the orthodontist and dental markets, which are deployed via a web-based service model on a pay per use basis. |
Cardiac Support Systems | US | Seed | Medical Devices Instrumentation | 2000 |
| Cardiac Support Systems was an innovation factory company. |
CardioFocus | US | Early Stage | Medical Devices Instrumentation | 1999 |
| CardioFocus is based in Marlborough, MA and has developed a catheter based approach using laser energy with visualization focused on atrial fibrillation. |
Celldex/Lorantis | UK | Start Up | Biotechnology Biopharmaceuticals | 2000 |
| Celldex merged with the quoted company Avant Immunotherapeutics (ticker:'AVAN') in March 2008. Celldex, formerly a wholly owned subsidiary of Medarex Inc., merged with Lorantis Ltd in 2005. Celldex pursues immunological approaches to the treatment of cancers, infectious disease and immunological disorders. |
Cellzome | Germany | Start Up | Biotechnology Biopharmaceuticals | 2001 |
| Cellzome is a drug discovery company building a R&D pipeline in chronic diseases by leveraging its unique drug proteomics engine. The business is based in Heidelberg, Germany and Cambridge, UK. |
Cerebral Vascular Applications | US | Seed | Medical Devices Instrumentation | 2000 |
| Cerebral Vascular Applications (TIF Company) has developed a set of minimally invasive tools for atrial appendage sealing for stroke prevention. |
Cognis | Luxembourg | Buyout | Biotechnology Biopharmaceuticals | 2001 |
| Cognis is a global supplier of innovative speciality chemicals for the cosmetics, detergents and cleaners industries and nutrional ingredients to the food and healthcare markets. |
Confluent Surgical | US | Early Stage | Medical Devices Instrumentation | 1999 |
| Confluent Surgical was a biomaterials for adhesion prevention and vascular embolics. |
EasyChem | US | Seed | Healthcare Services | 2000 |
| EasyChem was a B2B chemical e-commerce electronic marketplace. |
eMed Technologies | US | Expansion | Healthcare Services | 2000 |
| eMed Delivered medical images over the internet. |
Expand Sante | France | Seed | Healthcare Services | 2000 |
| Expand Sante was a French pharmaceutical contract sales organisation. |
Eyetech Pharmaceuticals | US | Early Stage | Biotechnology Biopharmaceuticals | 2000 |
| Eyetech was bought by OSI Pharmaceuticals after our exit through public markets. Opthalmolological drug development. |
IHG Holdings | US | Buyout | Healthcare Services | 2001 |
| IHG was a preferred provider organization. (Formerly known as Interplan). |
Ingenium | Germany | Early Stage | Biotechnology Biopharmaceuticals | 2000 |
| Ingenium was a functional genomics and drug development company. |
Insulet | US | Start Up | Medical Devices Instrumentation | 2001 |
| Insulet based in Bedford, MA, Insulet is designing and developing products that provide superior treatment for people with diabetes. The Company's first commercial product is a wireless 3-day insulin pump. |
KuDOS Pharmaceuticals | UK | Start Up | Biotechnology Biopharmaceuticals | 1999 |
| KuDOS was an oncology drug development company.
Acquired by Astra Zeneca in December 2005. |
LipoSonix | US | Seed | Medical Devices Instrumentation | 2001 |
| LipoSonix based in Bothell, WA, was developing a product to use non-invasive, high intensity focused ultrasound to ablate unwanted subcutaneous cells as a non-invasive alternative to liposuction for body sculpting.
Funded through the innovation factory. |
Mdeverywhere | US | Early Stage | Healthcare Services | 2001 |
| Mdeverywhere based in Hauppauge, NY with operations in New Dehli, India, is an outsourced physician billing company. |
Metris Therapeutics | UK | Start Up | Biotechnology Biopharmaceuticals | 2000 |
| Metris is a women's healthcare company that is developing drugs for the treatment of chronic gynecological and menstrual conditions. |
Orchid Chemicals and Pharmaceuticals | India | Expansion | Biotechnology Biopharmaceuticals | 1999 |
| Orchid manufactured bulk generic pharmaceuticals. |
Phase Forward | US | Expansion | Healthcare Services | 1999 |
| Phase Forward was a web-based information technology for clinical trials management. |
Physicians Dialysis | US | Buyout | Healthcare Services | 2001 |
| Physicians Dialysis was a consolidator of renal dialysis centers (Purchased by DaVita). |
Quantum Dot | US | Early Stage | Biotechnology Biopharmaceuticals | 2000 |
| Quantum Dot developed nanocrystal biological reagents. |
Quick Study Radiology | US | Start Up | Healthcare Services | 2000 |
| QSR based in St. Louis, MO, sells comprehensive digital imaging services to community hospitals and imaging centers. The company integrates, manages and supports clinical and data systems for customers with a focus on underserved small and secondary city locations. |
Solexa | UK | Start Up | Biotechnology Biopharmaceuticals | 2001 |
| Sold to Illumina ILMN.
Solexa used ultra high throughput DNA sequencing. |
Third Wave Technologies | US | Expansion | Biotechnology Biopharmaceuticals | 1999 |
| Third Wave developed products for analysing genetic variations. |
Trine Pharmaceuticals | US | Expansion | Biotechnology Biopharmaceuticals | 2001 |
| Trine, formerly Essential Therapeutics Inc., in-licenses, develops and plans to commercialize new classes of pharmaceutical products focused on renal, metabolic and GI clinical areas. |
Versicor | US | Expansion | Biotechnology Biopharmaceuticals | 1999 |
| Versicor was a drug development company for infectious diseases (Changed name to Vicurion Pharmaceuticals in 2003) |