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Medical Devices / InstrumentationPlease see below a list of all our SVLSF investments by sector. To go to individual portfolio companies websites please click on company logo. Medical Devices / Instrumentation
AcuFocus: US
First investment: 2001 - Seed AcuFocus is based in Irvine, CA, AcuFocus is developing an implantable corneal in-lay for correction of presbyopia. 
AqueSys: US
First investment: 2006 - Early Stage AqueSys is based in Duluth, GA; AqueSys (TIF company) is developing an innovative approach to reducing intra-ocular pressure to treat glaucoma. 
Argonaut Technologies: US - Exited
First investment: 1999 - Expansion Argonaut developed a chemistry instrumentation for accelerated synthesis of novel organic molecules. Bought by Biotage after our exit. 
Cardiac Support Systems: US - Exited
First investment: 2000 - Seed Cardiac Support Systems was an innovation factory company. 
CardioFocus: US
First investment: 1999 - Early Stage CardioFocus is based in Marlborough, MA and has developed a catheter based approach using laser energy with visualization focused on atrial fibrillation. 
Cardiomind: US
First Investment: 2007 - Early Stage CardioMind is a medical device company developing novel nitinol-based stents and an innovative, balloon-free stent delivery system for small, difficult-to-access vessels. 
Cellutions: US - Exited
First investment: 2004 - Seed Cellutions is based in Duluth, GA, (TIF)is developing a minimally invasive approach for addressing cellulite and its appearance on the skin. 
Cerebral Vascular Applications: US - Exited
First investment: 2000 - Seed Cerebral Vascular Applications incubated by TIF) developed a set of minimally invasive tools for atrial appendage sealing for stroke prevention. Licensed to Epitek. Funded through the innovation factory 
CHF Solutions: US
First investment: 2005 - Expansion CHF is based in Brooklyn Park, MN and has developed a mechanical pump/filter system to remove excess fluid from patients with acute de-compensated congestive heart failure. The product has US 510k clearance and is CE marked for both in-patient hospital care and out-patient clinic use. 
Concentric Medical: US
First investment: 2003 - Expansion Concentric is based in Mountain View, CA. Designing and developing products to open the pathway for stroke treatment. Their first device, the MERCI Retriever, removes clots associated with ischemic strokes. 
Confluent Surgical: US - Exited
First investment: 1999 - Early Stage Confluent Surgical was a biomaterials for adhesion prevention and vascular embolics. 
EBR Systems: US
First investment: 2005 - Early Stage EBR Systems is developing a wireless cardiac stimulation device (WiCS) to compete in the cardiac resynchronization therapy space for treatment of congestive heart failure. 
Entellus: US
First investment: 2006 - Early Stage Entellus is a company developing medical device therapies for nasal and sinus disease. 
Entellus: US
First investment: 2006 - Early Stage Entellus is a company developing medical device therapies for nasal and sinus disease. 
Eunoe: US - Exited
First investment: 2003 - Expansion Eunoe was a treatment of neurological disorders through cerebrospinal fluid management (CSF). 
General Surgical Innovations: US - Exited
First investment: 1995 - Early Stage General Surgical Innovations is a minimally invasive approach to hernia repair and incontinence (purchased by United States Surgical). 
Genosis: UK - Exited
First investment: 1999 - Start Up Genosis has developed home use diagnostic devices to assess fertility in couples of childbearing age. Genosis’ products - Fertell, which provide both male and female tests, are available over the counter in the UK and the US and provide couples with the tools required to assess their fertility in the privacy of their homes. 
Gyros: Sweden - Exited
First investment: 2002 - Start Up Gyros, located in Uppsala, Sweden, has developed a proprietary microfluidics technology for processing and analysis of proteins and blood samples. Laboratory processes are integrated into a client specific disc (CD) format. The CD is processed and its contents analysed on software controlled instrumentation. 
Halscion: US
First Investment: 2007 - Seed Halscion is seed-stage company founded by The Innovation Factory which is developing a biomaterial for wound management. 
Insulet: US - Exited
First investment SVLSF II: 2001 - Start Up Insulet based in Bedford, MA, Insulet is designing and developing products that provide superior treatment for people with diabetes. The Company’s first commercial product is a wireless 3-day insulin pump. 
Insulet: US - Exited
First investment SVLSF III: 2004 - Late Stage Insulet based in Bedford, MA, Insulet is designing and developing products that provide superior treatment for people with diabetes. The Company’s first commercial product is a wireless 3-day insulin pump. 
Leica Microsystems: Germany - Exited
First investment: 1998 - Buyout Leica Manufactured and marketed microscopes and neurosurgical equipment. 
LenSx Lasers, Inc: US
First Investment: 2008 - Start Up LenSx is developing a novel computer controlled, femtosecond laser system that can integrate multiple refractive surgical procedures performed in the cornea and lens. 
LipoSonix: US - Exited
First investment SVLSF II: 2001 - Seed First investment SVLSF III: 2003 - Seed LipoSonix based in Bothell, WA, was developing a product to use non-invasive, high intensity focused ultrasound to ablate unwanted subcutaneous cells as a non-invasive alternative to liposuction for body sculpting. Funded through the innovation factory. 
LipoSonix: US - Exited
First investment SVLSF II: 2001 - Seed First investment SVLSF III: 2003 - Seed LipoSonix based in Bothell, WA, was developing a product to use non-invasive, high intensity focused ultrasound to ablate unwanted subcutaneous cells as a non-invasive alternative to liposuction for body sculpting. Funded through the innovation factory. 
MedNova: Ireland - Exited
First investment: 1996 - Start Up MedNova was a device for interventional radiology and cardiology. 
Micromass: UK - Exited
First investment: 1996 - Buyout Micromass was a minimally invasive approach to hernia repair and incontinence (purchased by Waters). 
MicroMed: US - Exited
First investment: 1998 - Early Stage MicroMed based in Houston, TX, has developed an implantable pump for use as a Left Ventricular Assist Device (LVAD) to aid the heart’s pumping action in patients suffering from congestive heart failure. MindFrame: US First investment: 2007 - Seed MindFrame is a seed stage company formed out of Intersect Partners developing a novel mechanical device for the treatment of ischemic stroke. 
NeoVista: US
First investment: 2003 - Seed NeoVista based in Fremont, CA, is developing a surgical device for controlled irradiation to target tissue for arresting the progression of neovascularization, the cause of Wet AMD. Nexan: UK - Exited First investment: 1996 - Start Up Nexan was a remote telemonitoring devices. 
NovaLign: US
First investment: 2005 - Seed NovaLign based in Duluth, GA; is developing a minimally invasive implant for long bone fixation. Formerly know as OsteoLign. 
Ocular Therapeutix: US
First Investment: 2008 - Start Up I-Therapeutix is a medical device company that is currently engaged in development of in situ formed hydrogel therapeutic products specifically for ophthalmology. Formerly known as I-therapeutics . 
Orthovita: US - Exited
First investment: 1997 - Early Stage Orthovita was a novel bone substitute materials company. 
ReShape: US
First investment: 2005 - Seed ReShape is a seed stage project within the Intersect Partners incubator developing an endoscopically placed device for the treatment of obesity. 
ReShape: US
First investment: 2005 - Seed ReShape is a seed stage project within the Intersect Partners incubator developing an endoscopically placed device for the treatment of obesity. 
Sadra Medical: US
First investment: 2003 - Seed Sadra based in Campbell, CA, is developing an innovative new approach to aortic valve disease through a minimally invasive percutaneous replacement solution. 
Sadra Medical: US
First investment: 2003 - Seed Sadra based in Campbell, CA, is developing an innovative new approach to aortic valve disease through a minimally invasive percutaneous replacement solution. 
Sirona Dental Systems: Germany - Exited
First investment: 1997 - Buyout Sirona was a dental equipment manufacturer. 
Spinal Kinetics: US
First investment: 2005 - Early Stage Spinal Kinetics based in Redwood City, CA, is developing a 3rd generation artificial disc for cervical and lumbar spine surgery as an alternative to fusion. 
TransEnterix: US
First Investment: 2007 - Early Stage TransEnterix is developing a surgical platform that provides all the benefits of a multi-port laparoscopic surgical approach while retaining a single port of entry through a natural body orifice or via the umbilicus. 
ValenTx: US
First investment: 2009 - Early Stage ValenTx, Inc., a medical device company, develops less invasive treatments for morbid obesity. 
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